DESCRIPTION
ChromegaChiral™ CCO F2 is a tris(2-Fluoro 5-methylphenylcarbamate) cellulose phase which can be used in SFC or HPLC. The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting a fluorophilic retention mechanism which can provide improved retention for fluorinated compounds. A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine.
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