CYT17547303 - Cytiva - Resins - Chromatography - Lab supplies

: Catalog No. CYT17547303

Part No. 17547303
Supplier Cytiva

Capto Q XP 1 L

Net Price

4137

Availability

4 weeks

PROPERTIES

Chromatography technique

Ion Exchange Chromatography
Chemical stability

Commonly used aqueous buffers: 1 M sodium hydroxide, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol
Storage

20% ethanol at 4°C to 30°C
BioProcess resin

Yes
Ion Exchanger Type

Strong anion exchanger
Ionic Capacity

95 to 125 µmol Cl-/mL resin
Ligand

-OCH2CH(OH)CH2OCH2CH(OH)CH2N(CH3)3
Matrix

High-flow agarose
Pressure/Flow Specification

0.3 MPa at 700 cm/h, 1 m diameter column, 20 cm bed height
pH stability, CIP

2–14
pH stability, operational

2–12
Estimated shelf life from manufacture date

5 years
Flow velocity

Up to 300 cm/h in a 1 m diameter column with bed height 20 cm at 20°C; measured using process buffers with the same viscosity as water at < 3 bar (0.3 MPa)

DESCRIPTION

Capto Q XP is designed for capture and intermediate purification of large biomolecules, such as immunoglobulins IgG, IgM, IgA, in downstream processes. Efficient industrial-scale purification based on the well-established Capto platform with traditional ligands. Flexible process design due to large operational window of flow rates and bed heights. High throughput to improve manufacturing productivity and process economy. Excellent chemical stability. Resin fulfills industrial demands for security of supply, robust performance, and regulatory support. Useful for large biomoleculesCapto Q XP is based on a high-flow agarose base matrix with good pressure-flow properties and wide pore openings to give high available surface area for adsorption of large biomolecules. The Q ligand of the resin is well-established in large-scale purifications. The features of the base matrix, in combination with the conventional Q ligand, make Capto Q XP an excellent choice for high-productivity capture and intermediate purification of large biomolecules.Suited to large-scale productionCapto Q XP provides straightforward process development and many opportunities for improved productivity in industrial scales.Prepacked columns and other formatsCapto Q XP is available in the following formats: Lab/research scale – prepacked for manual purificationHiTrap Capto Q XP columns – for easy use with a syringe, peristaltic pump, or chromatography systemLab/research scale – prepacked for automated purification and analysisHiTrap Capto Q XP columns – for easy use with a syringe, peristaltic pump, or chromatography system.