A multimodal anion exchange resin designed for post-protein A purification of monoclonal antibodies at process scale. It can also be used in bind/elute mode. Wide operational window of pH and conductivity. Resin fulfills industrial demands for security of supply, robust performance, and regulatory support. Two-step chromatographic process with protein A affinity, saves time and cuts operating costs. Removes contaminants to formulation levels. High capacity and productivity in flow-through mode. Different selectivity from traditional IEX resins Capto adhere is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The strong multimodal ligand gives a different selectivity compared to traditional ion exchange (IEX) resins. Second step in mAb chromatographic process Capto adhere can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. Together with a Protein A capture step, like MabSelect SuRe, Capto adhere allows the design of a two-step chromatographic process for mAbs. Part of the Capto adhere family For optimal performance of Capto adhere, screening and optimization of loading conditions is recommended, preferably using modern high-throughput process development tools, such as PreDictor 96-well filter plates. Prepacked columns and other formats Capto adhere resin is available in the following formats:  Process development scale: prepacked PreDictor Capto adhere filter plates, 96-well plates for high-throughput screening or process development. PreDictor Capto adhere Robocolumn™ units, miniaturized columns for high-throughput process development. HiScreen Capto adhere columns, optimized for method and process development. Lab scale: prepacked for manual purification HiTrap Capto adhere columns, for easy use with a syringe, peristaltic pump, or chromatography system. Lab scale: prepacked for automated purification and analysis HiTrap Capto adhere columns, for easy use with a syringe, peristaltic pump, or chromatography system. Process characterization: resin kits Process Characterization Kit Capto adhere, designed for studying the potential impact that resin ligand density might have on the process outcome. Process-scale purification: prepacked ReadyToProcess Capto adhere columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.