DESCRIPTION
These chromatography columns are prepacked with MabSelect SuRe LX protein A resin for capture of monoclonal antibodies (mAbs) at process scale. ReadyToProcess columns are validated high-performance bioprocessing columns that are supplied prepacked and ready to use.
Alkaline-tolerant rProtein A ligand withstands rigorous cleaning and sanitization procedures with 0.1 to 0.5 M NaOH.
High dynamic binding capacity for high-titer monoclonal antibody capture.
Enables increased bioburden control.
MabSelect SuRe LX is a member of the MabSelect family of affinity resins for the capture of mAbs at process scale. MabSelect SuRe LX shares features and benefits of the MabSelect SuRe resin such as an alkaline stabilized protein A ligand, rigid, high-flow agarose matrix that ensures excellent pressure/flow properties, a low non-specific binding that leads to low impurity levels in the eluate pool, and an oriented ligand coupling for optimized protein binding capacity.
The enhanced alkaline-stability and high capacity of MabSelect SuRe LX improve process economy and product quality; cleaning can be performed with cost-effective reagents such as sodium hydroxide, eliminating the need for expensive and hazardous cleaning agents such as Gua-HCl.
The protein ligand construct of MabSelect SuRe LX has been proven to have an increased stability towards proteases. Therefore, the level of leakage of the MabSelect SuRe LX ligand during elution is low.
MabSelect SuRe has been demonstrated to give generic elution conditions for different monoclonal antibodies, which is an advantage when designing generic purification platform processes. This feature is also correlated to the construction of the MabSelect SuRe LX ligand.
Learn about MabSelect SuRe LX, prepacked HiScreen MabSelect SuRe LX, PreDictor MabSelect SuRe LX or PreDictor Robocolumns MabSelect SuRe LX
+852-3069 6950
sales@gugent.com.hk
