HiTrap Capto Q chromatography column is prepacked with a strong anion exchange modern resin for small scale protein purification. Suitable for screening of selectivity, binding and elution conditions, and for small-scale purifications. Quaternary ammonium (Q) strong anion exchanger. Optimized for capture and intermediate protein purification. Convenient HiTrap format for easy connection to a syringe, peristaltic pump, or chromatography system such as an ÄKTA system. Protein capture and intermediate purification with Capto Q resinCapto Q resin couples a quaternary ammonium (Q) strong anion exchanger to a chemically modified, high-flow agarose matrix. The rigid agarose matrix provides greater particle rigidity without compromising pore size, which allows for high bed volume and purification of viscous samples at high flow rates. High dynamic binding capacity is achieved with a dextran surface extender that coats the agarose matrix. The resin’s high binding-capacity, high flow rate, and low back pressure reduce process cycle times and improve productivity at process scale.Successful use in published researchResearch applications for this strong anion exchange resin include: The effects of a plant-produced vaccine candidate on Plasmodium falciparum transmissionAnalysis of outer membrane targeting of secretin PuID protein, and reliance on a dedicated chaperoneMolecular characterization ofPlasmodium falciparum uracil DNA glycosylaseOther Capto Q resin formatsThe resin in this prepacked column is also available as bulk resin and in other prepacked column formats. Therefore, it is possible to use the same resin for development work, pilot studies, and routine production.Other Cytiva ion exchange productsAmong Cytiva's solutions are a variety of ion exchange chromatography products, including, Capto, Sepharose, and SOURCE.