Fluorodyne™ II DBL membrane in Kleenpak™ Nova capsule, a Pall Life Sciences product, are encapsulated for higher flexibility while minimizing cleaning and installation costs. These 0.45 micron capsule filters are predominantly used in pre-filtration applications or viscous fluid filtrations. Validated removal of Serratia marcescens (ATCC 14756) with a typical titer reduction (TR) of > 106 ensures that they are also suitable for bioburden control. A serial layer (0.65/0.45 micron) membrane construction allows for high throughputs and high flow rates compared with other 0.45 micron-rated filters. Kleenpak Nova capsules are designed for use in medium-to-large-scale production environments (100 L to > 1000 L) and are often selected by the end-user following scaling studies using the smaller Kleenpak capsule formats.Kleenpak Nova capsules can be offered in ‘In-line’'(NP) or ‘T’style (NT) inlet/outlet configurations with sanitary flange or hose barb fittings. With the AB-style filter cartridge at their core, Kleenpak Nova filter capsules can be supplied with the most comprehensive range of filter media among all single-use capsules. Key Features and Benefits Encapsulated format for higher flexibility, minimized cleaning, and low installation costs Incorporated prefiltration layer Low extractables High protein transmission Rapid preservative recoveries Easy integrity testing Compatible with organic solvents, acids, and chemicals¹ Resin and surfactant-free Melt-sealed, non-shedding ¹ Except for ketones and amides Quality Standards Manufactured for use in conformance with cGMP 100% integrity tested ISO 9000 Certified Quality System Meets USP Biological Reactivity Test in vivo for Class VI-121°C plastics Every filter tested during manufacture Test correlated to microbial retention Certificate of Test provided includes Fabrication Integrity Bacterial Retention Materials of Construction Effluent quality for cleanliness, TOC and water conductivity, pH and pyrogens