AcroPak™ filters with Fluorodyne™ II membrane, a Pall Life Sciences product, are compatible with aqueous and many organic solvents Materials of construction Filter Media: Fluorodyne II membrane (hydrophilic PVDF) Housing, Vent Plug: Polypropylene Sealing Technology: Thermal bonding Filling Bell: Polycarbonate Pore Size 0.1 and 0.2 μm Effective Filtration Area 20 and 200 cm2 Dimensions (Nominal) AcroPak 20 Filters Housing Length: 8.3 cm (3.3 in.) Housing Diameter: 6.7 cm (2.7 in.) AcroPak 200 Capsule Overall Length: 10.5 cm (4.1 in.) Housing Diameter Without Vent: 5.3 cm (2.1 in.) Housing Diameter With Vent: 6.7 cm (2.6 in.) AcroPak 20 filters are designed to add convenience to small- and medium-volume filtrations AcroPak 200 Fluorodyne II capsules provide fast processing of clean batches Double layer sterilizing membrane enhances reliability Upstream air vent prevents vapor lock Manufactured without the use of adhesives to minimize extractables Pre-sterilized by gamma irradiation Inlet/Outlet Connections 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter stepped hose barb with female luer slip interior and filling bell outlet Maximum Operating Temperature and Pressure 60°C (140°F) at 1.0 bar (100 kPa, 15 psi) 4.1 bar (410 kPa, 60 psi) at 21 - 24°C (70 - 75°F) Recommended Integrity Test Minimum Bubble Point – Water 0.2 μm Fluorodyne II membrane: 3.2 bar (320 kPa, 46 psi) 60% IPA/40% H2O (v:v) 0.1 μm Fluorodyne II membrane: 1.8 bar (180 kPa, 26 psi) Typical Water Flow Rate mL/min at 0.1 bar (10 kPa) [mL/min/psi] AcroPak 20 Filters 0.1 μm Fluorodyne II Membrane: 13 (9) 0.2 μm Fluorodyne II Membrane: 26 (18) AcroPak 200 Capsule 0.2 μm Fluorodyne II Membrane: 240 (170) Typical Hold-Up Volume (with 10 psi air purge) AcroPak 20 Filters AcroPak 200 Capsule Bacterial Retention Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision Endotoxin Level Biological Safety Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo Sterilization Sterilized by gamma irradiation and individually packaged AcroPak 20 filters can withstand one autoclave cycle at 131°C (268°F) for 30 min Applications Sterile filtration of media and buffers Point-of-use filtration for lab water Suitable for viscous, particulate solutions and serum containing media Applicable for many fluids containing dilute proteins or preservatives Scalable Efficient processing volumes up to 20L. Fluorodyne II membrane is compatible with aqueous and many organic solvents. AcroPak 20 filters are designed to add convenience to small- and medium-volume filtrations.