AcroPak™ 500, 1000, & 1500 capsules with Supor™ membrane, a Pall Life Sciences product, deliver fast, final filtration and high throughputs for liquid volumes up to 150 L Provides higher throughputs and faster flow rates than similarly-sized competitive devices Ideal for solutions requiring low protein binding Saves money by increasing throughput with available built-in prefilter 100% integrity testing assures sterile filtrate 0.1 μm Supor membrane version reduces mycoplasma levels in cell culture media Fusion-welded components eliminate the potential for release of extractables from sealing adhesives Sterilization by gamma irradiation eliminates potential contamination by EtO residuals Materials of Construction Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane Housing, Vent Plug, and Filter Support: Polypropylene Sealing Technology: Thermal bonding Filling Bell: Polycarbonate Pore Size 0.1/0.1, 0.2/0.2, 0.8/0.2, and 0.8/0.45 μm Effective Filtration Area 500 Series: 500 cm2 1000 Series: 1000 cm2 1500 Series: 1500 cm2Dimensions Housing Diameter: 6.9 cm (2.7 in.) Overall Length (Without Filling Bell): 500 Series: 14.5 cm (5.7 in.) 1000 Series: 19.3 cm (7.6 in.) 1500 Series: 22.9 cm (9.0 in.) Inlet/Outlet Connections 500 and 1000 Series: 6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet 1500 Series: 12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet Typical Hold-Up Volume (with 10 psi air purge) 500 Series: 30 mL 1000 Series: 45 mL Maximum Operating Temperature 60°C (140°F) at 2.1 bar (210 kPa, 30 psi) Maximum Operating Pressure Continuous: 4.1 bar (410 kPa, 60 psi) at ambient temperature Recommended Integrity Test Minimum Bubble Point – Water 0.2 μm: 3.5 bar (350 kPa, 51 psi) 0.45 μm: 1.7 bar (170 kPa, 24 psi) 60% IPA/40% h3O (v:v) 0.1 μm: 2.4 bar (240 kPa, 35 psi) Bacterial Retention 0.1/0.1 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of A. laidlawii challenge per modified ASTM F838, current revision 0.2 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision Endotoxin Level Biological Safety Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo Sterilization Sterilized by gamma irradiation If desired, autoclave once only prior to use at 121 - 123°C (250 - 253°F) for a maximum of 20 min. Applications Large-volume media preparation Pilot-scale manufacturing Liquids requiring prefiltration, such as serum-containing media Sterile filtration of buffers Point-of-use filtration for laboratory water Reduce mycoplasma with the 0.1 µm pore size