AcroPak™ 200 capsules with Supor™ EKV membrane, a Pall Life Sciences product, provides additional debris holding, which makes them well suited for use with high turbidity, high bioburden solutions. Newer technology recommended for simplified scale-up High filtration area and compact size are ideal for upscale trials Minimal hold-up volume Good wettability for reliable integrity test Sealed membrane and housing uses fusion technology to eliminate potential extractables Gamma sterilized, non-pyrogenic, and provided with a removable filling bell (except sanitary flange option) Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility Very high flow rates and consistently higher total solution throughputs due to superior porosity over other membranes Materials of Construction Filter Media: Supor™EKV [hydrophilic polyethersulfone (PES)] membrane Housing, Vent Plug, and Support Material: Polypropylene Filling Bell: Polycarbonate (no filling bell on sanitary option) Sealing Technology: Thermal bonding without adhesives Pore Size 0.2 μm Effective Filtration Area 220 cm2Dimensions Housing Length: 12094: 10.5 cm (4.1 in.); 12095: 7.3 cm (2.9 in.) Housing Diameter: 5.3 cm (2.1 in.) without vent, 6.7 cm (2.6 in.) with vent Inlet/Outlet Connections 12094: 6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb inlet and outlet 12095: 13 mm (1/2 in.) sanitary flange inlet/outlet Typical Hold-Up Volume (with 10 psi air purge) Maximum Operating Temperature 60°C (140°F) at 2.1 bar (210 kPa, 30 psi) Maximum Operating Pressure 4.1 bar (410 kPa, 60 psi) at ambient temperature Recommended Integrity Test Minimum Bubble Point - Water > 3.32 bar (332 kPa, 48 psi) Typical Liquid Flow Rate 350 mL/min/0.1 bar (241 mL/min/psi) Bacterial Retention Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision Endotoxin Level Biological Safety Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo Sterilization Capsules that have been sterilized by gamma radiation can be autoclaved for 1 x 1/2hr cycle at 125°C. Applications Designed to quickly process difficultto- filter solutions within 5-21 L, such as serum, serum-supplemented culture media, and ascites fluid Ideal in situations where rapid filtration or short processing times are essential For buffers, tissue culture media, and other biological fluids. Newer technology recommended for simplified scale-up. High filtration area and compact size are ideal for upscale trials.