DESCRIPTION
ACQUITY UPLC M-Class Columns are designed for optimal performance for nano- to micro scale liquid chromatographic separation, offering the highest possible sensitivity, resolution and reproducibility for biomarker discovery and protein identification and characterization. As the 75µm to 180µm ID columns are fritted with a novel frit technology, they are able to withstand 15kpsi operating pressure and handle pressure fluctuations during injection extremely well and thus provide superior longevity. In order to achieve maximum performance, it is important to ensure that proper connections are made to minimize peak tailing and poor efficiency. This specific offering contains Waters HSS (High Strength Silica) Technology 100A pore, C18, 1.8um particles. The High Strength Silica particle overcomes the mechanical limitation of porous silica particles withstanding pressures for UPLC separations. The T3 bonding utilizes a trifunctional C18 Alkyl phase bonded at a ligand density that promotes polar compound retention and aqueous mobile phase compatibility.